Mechanisms of resistance to quinolones inSalmonellaTyphimurium from patients with infectious diarrhea
نویسندگان
چکیده
منابع مشابه
Mechanisms of resistance to quinolones.
The increased use of fluoroquinolones has led to increasing resistance to these antimicrobials, with rates of resistance that vary by both organism and geographic region. Resistance to fluoroquinolones typically arises as a result of alterations in the target enzymes (DNA gyrase and topoisomerase IV) and of changes in drug entry and efflux. Mutations are selected first in the more susceptible t...
متن کامل[Mechanisms of plasmid-mediated resistance to quinolones].
Quinolone resistance is caused mainly by chromosomal mutations in gram negative bacteria. In 1998, plasmid-mediated resistance to quinolones in clinical isolates was first reported in a Klebsiella pneumoniae strain. Locus qnr (quinolone resistance) was responsible of the quinolone resistance in this plasmid. qnr codes a protein whose function is protect both DNA-girase and topoisomerase IV from...
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Background and Objectives: Clostridium difficile is a gram-positive obligate anaerobic bacillus. Accurate and rapid diagnosis of this bacterium as well as assessment of its drug resistance pattern are one of the important issues in controlling infections caused by C. difficile. The purpose of the present study was to detect toxicogenic C. difficile and to evaluate drug resistance pattern of these...
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The introduction of chemotherapeutic agents, synthetic as well as those of natural origin, the antibiotics, has greatly altered the treatment and prognosis of infectious diseases. Despite these great advances in therapy, it must be borne in mind that many infections cannot be satisfactorily treated. In this group belong such diseases as the common cold, sinusitis, brucellosis, poliomyelitis, an...
متن کاملResistance to quinolones in mycobacteria.
Ohno, H., Koga, H., Kohno, S.. Higashiyama, Y., Miyazaki, Y., Ogawa, K., Yanagihra, K., Yamamoto, Y., Noda, T. & Miyamoto, J. (1994), Evaluation for rapid detection of rifampiein-rcsistant MycobacteHum tuberculosis by polymerase chain reaction-single strand conformation polymorphism. Kekkaku, 69, 773-778. Predieh, M., Doukhan, L., Nair, G. & Smith, I. (1995), Characterization of RNA polymerase ...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 2017
ISSN: 0385-5600
DOI: 10.1111/1348-0421.12476